Synaptophysin Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Synaptophysin |
| Clone | [EP10] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~38 kDa. Synaptophysin is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa (1). It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for the presynaptic vesicle, and functions in synaptic vesicle exocytosis, including cholesterol-dependent vesicle biogenesis, regulation of SNARE assembly via interaction with VAMP/synaptobrevin, formation of the fusion pore initiating neurotransmitter release, and activation of vesicle endocytosis (2, 3). This gene has also been implicated in X linked mental retardation (4). |
| Immunogen | Immunogen: Immunoprecipitate of human brain |
| Other Names | [Mouse Human Synaptophysin (native) IgG1; Synaptophysin (native) : APC/Cy7; SYPH; Sypl; Syn p38; Synaptophysin; Major synaptic vesicle protein p38] |
| Gene, Accession # | [SYPH], Gene ID: 6855, NCBI: NP_003170.1, UniProt: P08247 |
| Catalog # | MBS8002464 |
| Price | $460 |
| Order / More Info | Synaptophysin Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Johnston P.A., et al. (1989) J Biol Chem. 264: 1268-1273. 2. Thiele C., et al. (2000) Nat Cell Biol. 2: 42-49. 3. Valtorta F., et al. (2004) Bioessays 26: 445-453. 4. Tarpey P.S., et al. (2009) Nat Genet. 41(5): 535-543. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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