Mcl-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMcl-1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, dog, guinea pig, monkey, porcine, rabbit
Isotypen/a
Formatpeptide affinity purified
Size0.05 mg
Concentrationn/a
ApplicationsIF, IHC (PS), WB
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DescriptionRecognizes human, dog, guinea pig, monkey, pig and rabbit Mcl-1. Detects a band of ~42/43kDa by Western blot. Mcl-1 is a member of the Bcl-2 family that possesses anti-apoptotic activity. Mcl-1 is an immediate-early gene activated by the GMCSF as well as IL-3 signaling pathways and plays an important role in the viability response of these cytokines. Similar to all Bcl-2 family members, Mcl-1 contains BH1, BH2, and BH3 domains; however, unlike other members of this family, Mcl-1 has an extended N-terminal domain rich in PEST sequences, which probably accounts for the short half-life of this protein.
ImmunogenImmunogen: Synthetic peptide corresponding to a portion of human Mcl-1.
Other Names[Mcl-1], [MCL1; MCL1; TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; BCL2L3; Bcl2-L-3]
Gene, Accession #[Bcl-2-like protein 3], Gene ID: 4170, NCBI: Q07820.3, UniProt: Q07820
Catalog #MBS565335
Price$310
Order / More InfoMcl-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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