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Antigenic Specificity | RAB27A Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Ras-related protein Rab-27A is a protein that in humans is encoded by the RAB27A gene. The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Protein Function: Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. |
Immunogen | Immunogen: E Coli-derived human RAB27A recombinant protein (Position: L98-K216). Subcellular Localization: Membrane; Lipid-anchor. Melanosome. Tissue Specificity: Found in all the examined tissues except in brain. Low expression was found in thymus, kidney, muscle and placenta. Detected in melanocytes, and in most tumor cell lines examined. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells. |
Other Names | [Ras-related protein Rab-27A; Rab-27; GTP-binding protein Ram; RAB27A; RAB27] |
Gene, Accession # | [RAB27A], Gene ID: 5873, NCBI: NP_004571.2, UniProt: P51159 |
Catalog # | MBS1750678 |
Price | $315 |
Order / More Info | RAB27A Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |