CytokeRatin 18 / KeRatin K18 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CytokeRatin 18 / KeRatin K18 antibody, protein, ELISA kits.
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| Antigenic Specificity | CytokeRatin 18 / KeRatin K18 |
| Clone | [RGE53] |
| Host Species | Mouse |
| Reactive Species | dog, chicken,dog,hamster, human, mouse, rabbit, rat, porcine, zebrafish |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry , Immunoblotting, Immunocytochemistry, Immunohistochemistry (frozen), Western Blotting. |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: RGE53 reacts exclusively with Cytokeratin 18 which is present in glandular epithelial cells of the digestive, respiRatory, and urogenital tracts, endocrine and exocrine cells and mesothelial cells, as well as adenocarcinomas originating from them. Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in Human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual Human cytokeRatins are numbered 1 to 20. The various epithelia in the Human body usually express cytokeRatins which are not only characteristic of the type of epithelium, but a |
| Immunogen | Host Note: RGE53 is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0-AG14 mouse myeloma cells with spleen cells from a Mouse immunized with a cytoskeletal prepaRation of cells. |
| Other Names | [cytokeratin 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein; keratin 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18], [KRT18; KRT18; K18; CYK18; CYK18] |
| Gene, Accession # | Gene ID: 3875, UniProt: P05783 |
| Catalog # | MBS570157 |
| Price | $415 |
| Order / More Info | CytokeRatin 18 / KeRatin K18 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ramaekers, F., Huysmans, A., Moesker, O., Kant, A., Jap, P., Herman, C., and Vooijs, P. (1983). Monoclonal antibody to keRatin filaments, specific for glandular epithelia and their tumors. Use in surgical pathology, Lab Invest 49, 353-61. Ramaekers, F. C., Puts, J. J., Moesker, O., Kant, A., Huysmans, A., Haag, D., Jap, P. H., Herman, C. J., and Vooijs, G. P. (1983). Antibodies to intermediate filament proteins in the immunohistochemical identifiCation of Human tumours: an overview, Histochem J 15, 691-713. Puts, J. J., Moesker, O., Kenemans, P., Vooijs, G. P., and Ramaekers, F. C. (1985). Expression of cytokeRatins in early neoplastic epithelial lesions of the uterine cervix, Int J Gynecol Pathol 4, 300-13. Ramaekers, F., van Niekerk, C., Poels, L., Schaafsma, E., Huijsmans, A., Robben, H., Schaart, G., and Vooijs, P. (1990). Use of monoclonal antibodies to keRatin 7 in the differential diagnosis of adenocarcinomas, Am J Pathol 136, 641-55. Raats, J. M., Pieper, F. R., Vree Egberts, W. T., Verrijp, K. N., Ramaekers, F. C., and Bloemendal, H. (1990). Assembly of amino-terminally deleted desmin in vimentin-free cells, J Cell Biol 111, 1971-85. Smedts, F., Ramaekers, F., Robben, H., Pruszczynski, M., van Muijen, G., Lane, B., Leigh, I., and Vooijs, P. (1990). Changing patterns of keRatin expression during progression of cervical intraepithelial neoplasia, Am J Pathol 136, 657-68. Smedts, F., Ramaekers, F., Troyanovsky, S., Pruszczynski, M., Link, M., Lane, B., Leigh, I., Schijf, C., and Vooijs, P. (1992). KeRatin expression in cervical cancer, Am J Pathol 141, 497-511. van Leenders, G., Dijkman, H., Hulsbergen-van de Kaa, C., Ruiter, D., and Schalken, J. (2000). DemonstRation of intermediate cells during Human prostate epithelial differentiation in situ and in vitro using triple-staining confocal scanning microscopy, Lab Invest 80, 1251-8. |
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MYBIOSOURCE INC.
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