Edit |   |
---|---|
Antigenic Specificity | Human ApoE3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ApoE is a 34 kDa protein component of serum chylomicrons, VLDL, and HDL particles. It mediates the binding, uptake, and catabolism of these particles through interactions with the ApoE receptor and LDL receptors in the liver and brain. ApoE is important in fatty acid homeostasis and memory formation. Polymorphisms encode three variants (ApoE2, 3, 4) which are differentially related to the development of atherosclerosis and neurogenerative disorders. Mature human ApoE shares 71% amino acid sequence identity with mouse and rat ApoE. |
Immunogen | Antibody Generation: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hApoE3. Anti-Human ApoE3 specific antibody was purified by affinity chromatography employing immobilized hApoE3 matrix. *Cross Reactivity: human ApoE2, human ApoE4 in both western blot and sandwich ELISA. |
Other Names | [Antigen-Affinity Purified human ApoE3], [APOE; APOE; AD2; LPG; LDLCQ5; Apo-E] |
Gene, Accession # | [ApoE3], Gene ID: 348, NCBI: NP_000032.1, UniProt: P02649 |
Catalog # | MBS691379 |
Price | $415 |
Order / More Info | Human ApoE3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |