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Antigenic Specificity | Phospho-Beclin-1 (Ser90/93/96) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Beclin-1 (Ser90/93/96) Antibody detects endogenous levels of Beclin-1 only when phosphorylated at Ser90/93/96. Description: Plays a central role in autophagy (PubMed:23184933, PubMed:28445460). Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530, PubMed:26783301). Essential for the f |
Immunogen | Immunogen: A synthesized peptide derived from human Beclin-1 around the phosphorylation site of Ser90/93/96. Tissue Specificity: Ubiquitous. |
Other Names | [APG6; ATG 6; ATG6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; Beclin 1 (coiled coil moesin like BCL2 interacting protein); Beclin 1 autophagy related; Beclin-1; Beclin1; Becn1; BECN1_HUMAN; Coiled coil myosin like BCL2 interacting protein; Coiled-coil myosin-like BCL2-interacting protein; GT197; Protein GT197; VPS 30; VPS30] |
Gene, Accession # | [BECN1], Gene ID: 8678, NCBI: AAD27650.1, UniProt: Q14457 |
Catalog # | MBS9610748 |
Price | $225, $280, $340 |
Order / More Info | Phospho-Beclin-1 (Ser90/93/96) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |