TERT Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTERT
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: TERT antibody detects endogenous levels of total TERT. Function: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and rel
ImmunogenImmunogen: A synthetic peptide of human TERT Subcellular Location: Nucleus > Nucleolus. Nucleus > Nucleoplasm. Nucleus. Chromosome > Telomere. Cytoplasm. Nucleus > PML Body. Shuttling between nuclear and cytoplasm depends on cell cycle, phosphorylation states, transformation and DNA damage. Diffuse localization in the nucleoplasm. Enriched in nucleoli of certain cell types. Translocated to the cytoplasm via nuclear pores in a CRM1/RAN-dependent manner involving oxidative stress-mediated phosphor
Other Names[CMM9; DKCA2; DKCB4; EST2; HEST2; htert; hTRT; PFBMFT1; TCS1; Telomerase associated protein 2; Telomerase catalytic subunit; Telomerase reverse transcriptase; Telomerase-associated protein 2; Telomere Reverse Transcriptase; TERT; TERT_HUMAN; TP2; TRT]
Gene, Accession #[TERT], Gene ID: 7015, NCBI: NP_001180305.1, UniProt: O14746
Catalog #MBS9607780
Price$240, $280
Order / More InfoTERT Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBai C, Liu X, Xu J, Qiu C, Wang R, Zheng J; Journal: Hum Pathol. Expression profiles of stemness genes in gastrointestinal stromal tumor. Zhang Y, Chen Z, Wang T, Yang J, Li R, Wang S, Liu J, Ye Z; Journal: Oncotarget. Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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