TLR2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTLR2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionMembers of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses (1-3). TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated ac
ImmunogenImmunogen: Recombinant protein of human TLR2 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[TLR2; CD282; TIL4; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4]
Gene, Accession #[TLR2], Gene ID: 7097, NCBI: NP_001305716.1, UniProt: O60603
Catalog #MBS8500181
Price$310
Order / More InfoTLR2 Antibody from MYBIOSOURCE INC.
Product Specific References1. Akira, S. (2003) J Biol Chem 278, 38105-8. 2. Beutler, B. (2004) Nature 430, 257-63. 3. Dunne, A. and O'Neill, L.A. (2003) Sci STKE 2003, re3.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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