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Antigenic Specificity | Mouse VEGFR-2/Flk-1, soluble |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody recognizes mouse vascular endothelial growth factor receptor 2, alos known as CD309, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle; other tissues express at lower levels. Flk-1 is a receptor for VEGF-A or fully processed VEGF-C; ligand binding plays a key role in vascular development and vascular permeability. |
Immunogen | Immunogen: Recombinant mouse esFlk-1 (RT Cat# S01-M04). Preparation: Produced from sera of rabbits immunized with highly pure recombinant mouse soluble endogenous Flk-1 (Ala20 - Pro673) as the immunizing antigen. |
Other Names | [mouse VEGFR-2/Flk-1; Vascular endothelial growth factor receptor 2; Protein-tyrosine kinase receptor flk-1], [Kdr; Kdr; Flk1; Ly73; Flk-1; Krd-1; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07; Flk-1; Flk1; VEGFR-2; FLK-1] |
Gene, Accession # | [VEGFR-2/Flk-1], Gene ID: 16542, NCBI: ACJ66293.1, UniProt: P35918 |
Catalog # | MBS691171 |
Price | $390 |
Order / More Info | Mouse VEGFR-2/Flk-1, soluble Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Shibata et al, BMC Medicine 8 (2010) 2. Albaquerque et al, Nature Med 2009 3. Ebos et al, Mol Cancer Res 2 (2004) 4. Ebos et al, Cancer res 68 (2008). |