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Antigenic Specificity | Human Lymphotoxin-alpha |
Clone | [PAT15A3AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2bheavy chain and k ligth chain. |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: Lymphotoxin-alpha (LT-alpha or LTA) belongs to the TNF ligand superfamily, which bind the same TNF receptor and mediate similar pleiotropic effect. LTA is a proinflammatory cytokine with important biological activity and immunomodulatory function and is known to influence a variety of cellular response. Furthermore, LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and has a role in apoptosis. LTA is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. LTA, which is located within the MHC III region of chromosome 6, shows close relation to |
Immunogen | Immunogen: Anti-human LTA mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LTA amino acids 35-205 purified from E Coli. |
Other Names | [LTA; Lymphotoxin-alpha, Mouse Human; Lymphotoxin-alpha; LT-alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1; LTA; TNFB; TNFSF1; LT], [LTA] |
Gene, Accession # | [LTA], NCBI: Q6FG55 |
Catalog # | MBS140345 |
Price | $140, $205, $505 |
Order / More Info | Human Lymphotoxin-alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |