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Antigenic Specificity | EGF R (pSer1046) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti EGF R (pSer1046) antibody recognizes the epidermal growth factor receptor (EGF R), also known as proto-oncogene c-ErbB-1 or receptor tyrosine-protein kinase erbB-1, when phosphorylated at serine 1046. EGF R is a transmembrane glycoprotein and a member of the ErbB receptor tyrosine kinase family. EGFR is a cell surface receptor for members of the epidermal growth factor family. EGF R plays a role in numerous cellular processes such as cell proliferation and apoptosis through the activation of downstream signaling pathways (Scaltriti and Baselga 2006). EGF R is autophosphorylated at serine 1046 and serine 1047 upon ligand binding and receptor dimerization. Phosphorylation of serine 1046 and serine 1047 plays an important role in E |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine1046 of human EGF R |
Other Names | [EGF R (pSer1046)], [EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; ERBB; ERBB1; HER1] |
Gene, Accession # | [EGFR], Gene ID: 1956, NCBI: P00533.2, UniProt: P00533 |
Catalog # | MBS225225 |
Price | $375 |
Order / More Info | EGF R (pSer1046) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |