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Antigenic Specificity | HLA-DRA, 48-75 |
Clone | [302CT2.3.2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HLA-DRA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 48-75 amino acids from human HLA-DRA. HLA-DRA is one of the HLA class II alpha chain paralogues.This class II molecule is a heterodimer consisting of an alpha anda beta chain, both anchored in the membrane. It plays a centralrole in the immune system by presenting peptides derived fromextracellular proteins. Class II molecules are expressed in antigenpresenting cells (APC: B lymphocytes, dendritic cells,macrophages). The alpha chain is approximately 33-35 kDa and itsgene contains 5 exons. Exon 1 encodes the leader peptide, exons 2and 3 encode the two extracellular domains, and exon 4 encodes thetransmemb |
Immunogen | n/a |
Other Names | [HLA class II histocompatibility antigen; DR alpha chain; MHC class II antigen DRA; HLA-DRA; HLA-DRA1] |
Gene, Accession # | [HLA-DRA], Gene ID: 3122, NCBI: NP_061984.2, UniProt: P01903 |
Catalog # | MBS9200177 |
Price | $370 |
Order / More Info | HLA-DRA, 48-75 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010) Hamza, T.H., et al. Nat. Genet. 42(9):781-785(2010) Iwasa, K., et al. J. Neuroimmunol. 225 (1-2), 171-174 (2010) : Jin, Y., et al. N. Engl. J. Med. 362(18):1686-1697(2010) |