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Antigenic Specificity | Phospho-RelB (Ser552) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-RelB (Ser552) antibody detects endogenous levels of RelB only when phosphorylated at Serine 552. Description: RelB a transcription factor of the nuclear factor-kappaB (NFkB) transcription complex. Stimulates promoter activity in the presence NFkB1/NFkB-p50. Plays role in regulation of apoptosis in hepatocellular carcinoma through activation of downstream target genes.Function: NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo-or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/ |
Immunogen | Immunogen: A synthesized peptide derived from human RelB around the phosphorylation site of Serine 552 Subcellular Location: Nucleus. Cytoplasm > Cytoskeleton > Centrosome. Co-localizes with NEK6 in the centrosome. Tissue Specificity: Up-regulated by mitogens and NUPR1. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (90%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%) |
Other Names | [I REL; I-Rel; IREL; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; relB; RELB_HUMAN; Reticuloendotheliosis viral oncogene homolog B; Transcription factor Rel B; Transcription factor RelB; v rel avian reticuloendotheliosis viral oncogene homolog B; v rel reticuloendotheliosis viral oncogene homolog B] |
Gene, Accession # | [RelB], Gene ID: 5971, NCBI: NP_006500.2, UniProt: Q01201 |
Catalog # | MBS9601149 |
Price | $240, $280 |
Order / More Info | Phospho-RelB (Ser552) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |