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Antigenic Specificity | ANGPT5 |
Clone | [AT23D8] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, k |
Format | Protein A purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ANGPTL3 also known as Angiopoietin-related protein 3 is a member of the angiopoietin-like family of secreted factors. It is expressed predominantly in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain, and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. |
Immunogen | Immunogen: Recombinant human ANGPT5 (243-460aa) purified from E. coli. |
Other Names | [Angiopoietin-related protein 3; ANG-5; ANGPT5; ANL3; FHBL2], [ANGPTL3; ANGPTL3; ANL3; ANG-5; FHBL2; ANGPT5; ANGPT5; ANG-5] |
Gene, Accession # | [ANGPT5], Gene ID: 27329, NCBI: NP_055310, UniProt: Q9Y5C1 |
Catalog # | MBS206594 |
Price | $240, $315 |
Order / More Info | ANGPT5 Antibody from MYBIOSOURCE INC. |
Product Specific References | Arca M., et al. (2013) Curr. Opin. Lipidol. 24 (4): 313-20.; Quagliarini F Q., et al. (2012) Proc Natl Acad Sci. 109 (48): 19751-6. |