Mouse Dyrk2 (C-term), 521-549 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Mouse Dyrk2 (C-term), 521-549 antibody, protein, ELISA kits.
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| Antigenic Specificity | Mouse Dyrk2 (C-term), 521-549 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Dyrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of mouse Dyrk2. Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates (By similarity). |
| Immunogen | n/a |
| Other Names | [Dual specificity tyrosine-phosphorylation-regulated kinase 2; Dyrk2 {ECO:0000312|MGI:MGI:1330301}] |
| Gene, Accession # | [Dyrk2], Gene ID: 69181, NCBI: NP_001014412.1, UniProt: Q5U4C9 |
| Catalog # | MBS9206856 |
| Price | $165, $370 |
| Order / More Info | Mouse Dyrk2 (C-term), 521-549 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Guo, X., et al. J. Biol. Chem. 285(17):13223-13232(2010) Kudo, L.C., et al. Cereb. Cortex 17(9):2108-2122(2007) Blackshaw, S., et al. PLoS Biol. 2 (9), E247 (2004) : Clark, A.G., et al. Science 302(5652):1960-1963(2003) Geiger, J.N., et al. Blood 97(4):901-910(2001) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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