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Antigenic Specificity | MAP3K2 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MAP3K2 antibody detects endogenous levels of total MAP3K2. Description: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates the kinases involved in the MAP kinase signaling pathway including MAPK7 and MAP2K4. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases (IKKs), and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2 (PRKCL2/PRK2), which suggests its involvement in PRKCL2 regulated signaling process.Function: Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activa |
Immunogen | Immunogen: Purified recombinant fragment of human MAP3K2 expressed in E. Coli Subcellular Location: Nucleus |
Other Names | [M3K2_HUMAN; Map3k2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2; MEKK2b; Mitogen activated protein kinase kinase kinase 2; Mitogen-activated protein kinase kinase kinase 2] |
Gene, Accession # | [MAP3K2], Gene ID: 10746, NCBI: NP_006600.3, UniProt: Q9Y2U5 |
Catalog # | MBS9602591 |
Price | $235, $295, $370 |
Order / More Info | MAP3K2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |