HERP Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HERP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: HERP antibody detects endogenous levels of HERP. Function: Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated amyloid-beta protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway (PubMed:18307982).Subunit Structure: Interacts with PSEN1 and PSEN2. Interacts with SYVN1 and UBXN6. Interacts with UBQLN1, UBQLN2 and UBQLN4. |
| Immunogen | Immunogen: A synthesized peptide derived from human HERP. Subcellular Location: Endoplasmic Reticulum Membrane. Tissue Specificity: Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (92%), Horse (100%), Sheep (92%), Rabbit (100%), Dog (100%) |
| Other Names | [HERP; HERP1_HUMAN; HERPUD1; Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 1; Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 1 protein; Homocysteine responsive endoplasmic reticulum resident ubiquitin like domain member 1; Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; KIAA0025; Methyl methanesulfonate (MMF) inducible fragment protein 1; Methyl methanesulfonate (MMF)-inducible fragment protein 1; MIF1; MMS inducible; SUP] |
| Gene, Accession # | [HERP], Gene ID: 9709, NCBI: NP_001010989.1, UniProt: Q15011 |
| Catalog # | MBS9603506 |
| Price | $240, $280 |
| Order / More Info | HERP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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