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Antigenic Specificity | ARHGAP22 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ARHGAP22 antibody detects endogenous levels of total ARHGAP22. Function: Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity).Subunit Structure: Interacts with VEZF1. |
Immunogen | Immunogen: A synthesized peptide derived from human ARHGAP22 Subcellular Location: Cytoplasm. Nucleus. Mainly cytoplasmic. Some fraction is nuclear. |
Other Names | [ARHGAP22; RHG22_HUMAN; Rho GTPase activating protein 2; Rho GTPase activating protein 22; Rho GTPase-activating protein 22; Rho type GTPase activating protein 22; Rho-type GTPase-activating protein 22; RhoGAP2; RhoGap22] |
Gene, Accession # | [ARHGAP22], Gene ID: 58504, NCBI: NP_001242953.1, UniProt: Q7Z5H3 |
Catalog # | MBS9602055 |
Price | $240, $280 |
Order / More Info | ARHGAP22 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |