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Antigenic Specificity | PLEKHM3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PLEKHM3 Antibody: PLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins. PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2. In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions. Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis. |
Immunogen | Immunogen: PLEKHM3 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human PLEKHM3. Buffer: PLEKHM3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [PLEKHM3; DAPR; PLEKHM1L; Pleckstrin homology domain-containing family M member 3; PH domain-containing family M member 3; pleckstrin homology domain containing, family M, member 3], [PLEKHM3; PLEKHM3; DAPR; PLEKHM1L; PLEKHM1L; PH domain-containing family M member 3] |
Gene, Accession # | [PLEKHM3], Gene ID: 389072, NCBI: Q6ZWE6.2, UniProt: Q6ZWE6 |
Catalog # | MBS151324 |
Price | $375 |
Order / More Info | PLEKHM3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |