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Antigenic Specificity | Mouse CD18 |
Clone | [C71/16] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunohistochemistry (Frozen Sections); Immunoprecipitation; Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Common beta 2 subunit (Mr 95 kDa) of the LFA-1 integrin complex. CD18 represents the common beta 2 integrin subunit that associates non-covalently with the alpha beta chains of CD11a/LFA-1a, CD11b/Mac-1, and CD11c to form various integrin heterodimers. It is expressed strongly on lymphocytes and monocytes, and weakly on granulocytes, CD18 mediates a variety of heterotypic and homotypic intercellular adhesion reactions, and it regulates the ligand-binding activities of the various CD11/CD18 complexes. MAb C71/16 has not been reported to inhibit cell adhesion.^1-4. |
Immunogen | Immunogen: Cell membrane lysates derived from mouse T cell lymphoma BW5147 |
Other Names | [Rat Mouse CD18 - Purified, Unlabeled; Rat Mouse CD18/Integrin beta 2 Chain], [LOC100304487] |
Gene, Accession # | Gene ID: 100304487 |
Catalog # | MBS673230 |
Price | $260 |
Order / More Info | Mouse CD18 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Trowbridge, I. and M.B. Omary, 1981. J. Exp. Med. 154:1517.2. Mazzone, A. and G. Ricevuti. Haemotoligica, 80:161.3. Lub, M., Y. van Kooyk, and C. G. Figdor, 1995. Immunol. Today. 16:479.4. Springer, T.A., G. Galfre, D.S. Secher, and C. Milstein. 1978. Eur. J. Immunol. 8:539. |