Edit |   |
---|---|
Antigenic Specificity | AUH |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities. The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA, a critical step in the leucine degradation pathway. This protein also binds AU-rich elements (AREs) found in the 3' UTRs of rapidly decaying mRNAs including c-fos, c-myc and granulocyte/macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis. Mutations in this gene are the cause of 3-me |
Immunogen | Immunogen: Recombinant protein of human AUH Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [methylglutaconyl-CoA hydratase, mitochondrial isoform 2; Methylglutaconyl-CoA hydratase, mitochondrial; methylglutaconyl-CoA hydratase, mitochondrial; AU RNA binding methylglutaconyl-CoA hydratase; AU-specific RNA-binding enoyl-CoA hydratase; AU-binding protein/enoyl-CoA hydratase; Itaconyl-CoA hydratase] |
Gene, Accession # | [AUH], Gene ID: 549, NCBI: NP_001293119.1, UniProt: Q13825 |
Catalog # | MBS8536373 |
Price | $300 |
Order / More Info | AUH Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |