RIP1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RIP1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | RIP1 Antibody: RIP1 (Receptor Interacting Protein), also known as RIPK1, is a crucial 74 kD adaptor kinase in several of stress-induced signaling pathways and on the crossroad of a cell's decision to live or die. RIP1 contains an N-terminal region with homology to protein kinases, an intermediate domain capable of association with MAPKKK and a C-terminal region containing a death domain motif present in the Fas and TNFR1 intracellular domains. Full length RIP1 is important for signallling to NF-kappa-B, MAPKs and necrosis, whereas caspase-8 generates a C-terminal RIP1 cleavage fragment, promoting TNF-induced apoptosis. It is required for TNFRSF1A-mediated and TLR3-induced NF-kappa-B activation. RIP1-deficient mice fail to thrive, displaying |
| Immunogen | Immunogen: RIP1 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human RIP1. Buffer: RIP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [RIP1; RIP; RIP1; RIP; Cell death protein RIP; RIP-1; receptor (TNFRSF)-interacting serine-threonine kinase 1], [RIPK1; RIPK1; RIP; RIP1; RIP; RIP1; RIP-1] |
| Gene, Accession # | [RIPK1], Gene ID: 8737, NCBI: NP_003795, UniProt: Q13546 |
| Catalog # | MBS153546 |
| Price | $375 |
| Order / More Info | RIP1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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