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Antigenic Specificity | ITGAD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ITGAD antibody detects endogenous levels of total ITGAD. Function: Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood.Subunit Structure: Heterodimer of an alpha and a beta subunit. Alpha-D associates with beta-2.Similarity: The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. Belongs to the integrin alpha chain family. |
Immunogen | Immunogen: A synthesized peptide derived from human ITGAD Subcellular Location: Plasma Membrane Tissue Specificity: Expressed moderately on myelomonocytic cell lines and subsets of peripheral blood leukocytes and strongly on tissue-specialized cells, including macrophages foam cells within atherosclerotic plaques, and on splenic red pulp macrophages. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog Similarity: Bovine (82%), Horse (91%), Sheep (82%), Rabbit (91%), Dog (100%) |
Other Names | [ADB2; FLJ39841; integrin alpha D] |
Gene, Accession # | [ITGAD], Gene ID: 3681, NCBI: NP_001305114.1, UniProt: Q13349 |
Catalog # | MBS9609312 |
Price | $240, $280 |
Order / More Info | ITGAD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |