Edit |   |
---|---|
Antigenic Specificity | ESRRB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Isoform 3: Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter and enhancer of targets genes regulating their expression or their transcription activity (PubMed:17920186, PubMed:19755138). Plays a role, in a LIF-independent manner, in maintainance of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways. Upon FGF signaling pathway activation, interacts with KDM1A by directly binding to enhancer site of ELF5 and EOMES and activating their transcription leading to self-renewal of trophoblast stem cells. Also regulates expression of multiple rod-specific genes and is requ |
Immunogen | Immunogen: Recombinant Human Steroid hormone receptor ERR2 protein (432-502AA) |
Other Names | [Steroid hormone receptor ERR2; ERR beta-2; Estrogen receptor-like 2; Estrogen-related receptor beta1; ESRRB] |
Gene, Accession # | [ESRRB], Gene ID: 2103, NCBI: NP_004443.3, UniProt: O95718 |
Catalog # | MBS7107863 |
Price | $160, $235 |
Order / More Info | ESRRB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |