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Antigenic Specificity | STAT4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: STAT4 (phospho-Tyr693) antibody detects endogenous levels of STAT4 only when phosphorylated at tyrosine 693. This gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provi |
Immunogen | Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human STAT4 around the phosphorylation site of tyrosine 693 (K-G-YP-V-P). |
Other Names | [signal transducer and activator of transcription 4; Signal transducer and activator of transcription 4; signal transducer and activator of transcription 4; signal transducer and activator of transcription 4], [STAT4; STAT4; SLEB11] |
Gene, Accession # | [STAT4], Gene ID: 6775, NCBI: NP_003142.1 |
Catalog # | MBS417422 |
Price | $325 |
Order / More Info | STAT4 Antibody from MYBIOSOURCE INC. |
Product Specific References | Strausberg R L, et al. (2002) Proc Natl Acad Sci U S A. 99(26):16899-16903. |