Phospho-GSK3 alpha/beta (Tyr279/216) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-GSK3 alpha/beta (Tyr279/216) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-GSK3 alpha/beta (Tyr279/216) antibody detects endogenous levels of GSK3 alpha/beta only when phosphorylated at Tyrosine 279/216. Description: GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.Function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosp |
| Immunogen | Immunogen: A synthesized peptide derived from human GSK3 alpha/beta around the phosphorylation site of Tyrosine 279/216 Subcellular Location: Cytoplasmic and Nuclear Predicted Cross Reactivity: Pig, Bovine, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Chicken (100%), Xenopus (100%) |
| Other Names | [DKFZp686D0638; Glycogen synthase kinase 3 alpha; Glycogen synthase kinase-3 alpha; GSK 3 alpha; GSK 3A; GSK-3 alpha; Gsk3a; GSK3A_HUMAN; GSK3alpha; Serine/threonine protein kinase GSK3A] |
| Gene, Accession # | [GSK3A], Gene ID: 2931, NCBI: NP_063937.2, UniProt: P49840 |
| Catalog # | MBS9601104 |
| Price | $240, $280 |
| Order / More Info | Phospho-GSK3 alpha/beta (Tyr279/216) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Salimian N, Peymani M, Ghaedi K, Nasr Esfahani MH; Journal: Gene. Modulation in miR-200a/SIRT1axis is associated with apoptosis in MPP -induced SH-SY5Y cells. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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