HIRA (Center), 431-461 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHIRA (Center), 431-461
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: chicken, mouse, Xenopus)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis HIRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-461 amino acids from the Central region of human HIRA. HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embr
Immunogenn/a
Other Names[Protein HIRA; TUP1-like enhancer of split protein 1; HIRA; DGCR1; HIR; TUPLE1]
Gene, Accession #[HIRA], Gene ID: 7290, NCBI: NP_003316.3, UniProt: P54198
Catalog #MBS9214151
Price$165, $370
Order / More InfoHIRA (Center), 431-461 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesZhang,R., Mol. Cell. Biol. 27 (6), 2343-2358 (2007) Tang,Y., Nat. Struct. Mol. Biol. 13 (10), 921-929 (2006)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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