Mouse CD278 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD278
Clone[C398.4A]
Host SpeciesHamster
Reactive Specieshuman, porcine, rat
IsotypeIgG
Formatunconjugated
Size0.25 mg
ConcentrationIgG concentration 0.5mg/ml
ApplicationsImmunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP)
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DescriptionThis item recognises CD278, also known as Inducible T cell costimulator or ICOS, a CD28-superfamily costimulatory molecule. It is expressed on activated T cells and resting memory T cells. It enhances all the basic T cell responses to a foreign antigen, namely proliferation, secretion of lymphokines and up-regulation of molecules that mediate cell-cell interaction. It is essential for the efficient interaction between B and T cells and is involved in antibody responses to T cell dependent antigens. It up-regulates the synthesis of interleukin-10, but not interleukin-2 and prevents the apoptosis of pre-activated T cells. Clone C398.4A has been reported to costimulate T cell activation and proliferation in vitro. MBS219570 recognises CD278, a
ImmunogenImmunogen: Mouse T cell clone D10.G4.1 Buffer Solution: Phosphate buffered saline Target Species: Mouse
Other Names[inducible T-cell costimulator; Inducible T-cell costimulator; inducible T-cell costimulator; activation-inducible lymphocyte immunomediatory molecule; inducible costimulator; inducible T-cell co-stimulator; Activation-inducible lymphocyte immunomediatory molecule; CD_antigen: CD278], [ICOS; ICOS; AILIM; CD278; CVID1; AILIM]
Gene, Accession #[CD278], Gene ID: 29851, NCBI: NP_036224.1
Catalog #MBS219570
Price$430
Order / More InfoMouse CD278 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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