Cyclin D1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Cyclin D1 antibody, protein, ELISA kits.
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| Antigenic Specificity | Cyclin D1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | G1/S-specific cyclin-D1 is a protein that in humans is encoded by the CCND1 gene. Cyclin D1 belongs to the core cell cycle machinery, and it is frequently overexpressed in human cancers.1 Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle. CCND1 associates with and regulates transcription factors, coactivators, and corepressors that govern histone acetylation and chromatin remodeling proteins. CCND1 also has roles in cellular growth, metabolism, and cellular differentiation. Amplification or overexpression of cyclin D1 plays pivotal roles in the development of a subset of human cancers including parathyroid |
| Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to near the C-terminal of mouse Cyclin D1. |
| Other Names | [Cyclin D1], [cyclin D1] |
| Gene, Accession # | NCBI: CAA54800.1, UniProt: Q9H014 |
| Catalog # | MBS355078 |
| Price | $275 |
| Order / More Info | Cyclin D1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Bienvenu, F., Jirawatnotai, S., Elias, J. E., Meyer, C. A., Mizeracka, K., Marson, A., Frampton, G. M., Cole, M. F., Odom, D. T., Odajima, J., Geng, Y., Zagozdzon, A., Jecrois, M., Young, R. A., Liu, X. S., Cepko, C. L., Gygi, S. P., Sicinski, P. Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen. Nature 463: 374-378, 2010. 2. Fu, M., Wang, C., Li, Z., Sakamaki, T., Pestell, R. G. Minireview: Cyclin D1: normal and abnormal functions. Endocrinology 145: 5439-5447, 2004. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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