TAK1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | TAK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat. |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase kinase kinase 7 (MAP3K7) detection. Background: Mitogen-activated protein kinase kinase kinase 7, also known as TAK1, is an enzyme that in humans is encoded by the MAP3K7 gene. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MA |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TAK1 (566-603aa RLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQ), identical to the related mouse and rat sequences. |
| Other Names | [MAP3K 7; MAP3K7; MEKK7; TAK1; TGF1a; O43318; Mitogen-activated protein kinase kinase kinase 7], [MAP3K7; MAP3K7; TAK1; MEKK7; TGF1a; TAK1; TGF-beta-activated kinase 1] |
| Gene, Accession # | [MAP3K7], Gene ID: 6885, NCBI: NP_003179.1, UniProt: O43318 |
| Catalog # | MBS178506 |
| Price | $280 |
| Order / More Info | TAK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: MAP3K7 mitogen-activated protein kinase kinase kinase 7.2. Kondo M, Osada H, Uchida K, Yanagisawa K, Masuda A, Takagi K, Takahashi T, Takahashi T (February 1998). Molecular cloning of human TAK1 and its mutational analysis in human lung cancer. Int J Cancer 75 (4): 559-63.3. Ninomiya-Tsuji J, Kishimoto K, Hiyama A, Inoue J, Cao Z, Matsumoto K (March 1999). The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway.Nature 398 (6724): 252-6. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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