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Antigenic Specificity | RhoA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total RhoA antibody. Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the exchange of bound GDP for GTP, and inhibited by GTPase activating proteins (GAPs), which catalyze the hydrolysis of GTP to GDP. A third level of regulation is provided by the stoichiometric binding of Rho GDP dissociation inhibitor (RhoGDI) (1). RhoA, RhoB and RhoC are highly homologous, but appear to have divergent biological functions. Carboxy-terminal modifications and differences in subcellular localization allow these thr |
Immunogen | Immunogen Type: Peptide Immunogen Description: Center-peptide of human RhoA. |
Other Names | [RHOA; ARH12; ARHA; RHO12; RHOH12] |
Gene, Accession # | [RhoA], Gene ID: 387, NCBI: NP_001655.1, UniProt: P61586 |
Catalog # | MBS9404261 |
Price | $255 |
Order / More Info | RhoA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |