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Antigenic Specificity | CD27 (Tumor Necrosis Factor Receptor Superfamily 7) |
Clone | [203.6] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG3, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis. |
Immunogen | Immunogen: Sezary cells |
Other Names | [LPFS2; S152; T cell activation antigen S152; T-cell activation antigen CD27; T14; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7], [CD27; CD27; T14; S152; Tp55; TNFRSF7; S152. LPFS2; TNFRSF7] |
Gene, Accession # | [CD27], Gene ID: 939, NCBI: NP_001233.1, UniProt: P26842 |
Catalog # | MBS438884 |
Price | $190, $340, $340 |
Order / More Info | CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kishimoto T et al. (eds) Leukocyte Typing VI. P67-71, Garland Publishing, New York, 1997 |