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Antigenic Specificity | CAMK4 (CaMKIV) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of CAMK4 and does not cross-react with related proteins. UniPort Summary Function: Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consodilation. In the thymus, regulates the CD4+/CD8+ double positive thymocytes selection threshold during T-cell ontogeny. In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2). Regulates the differentiat |
Immunogen | Immunogen: Purified recombinant human CAMK4 protein fragments expressed in E Coli. Cellular Localization: Cytoplasm; Nucleus |
Other Names | [CaM kinase-GR], [IV; caMK; CaMK IV; CaMK-GR] |
Gene, Accession # | [CAMK4], Gene ID: 814, NCBI: NP_001310303.1, UniProt: Q16566 |
Catalog # | MBS857733 |
Price | $300 |
Order / More Info | CAMK4 (CaMKIV) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |