Acetylated Lysine Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAcetylated Lysine
Clonepolyclonal
Host SpeciesRabbit
Reactive SpeciesGeneral
Isotypen/a
FormatAPC-Cy7 conjugate
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA (EIA)
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DescriptionDetects proteins containing acetylated lysine residues. No reaction to non-acetylated proteins. Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common post-transcriptional modification of Lysine involves acetylation (1). The conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) (2). Protein posttranslational reversible lysine Nepsilon-acetylation and deacetylation have been recognized as an emerging intracellular signaling mechanism that
ImmunogenImmunogen: Acetylated KLH Conjugated
Other Names[Rabbit Acetylated Lysine; lysine; acetyl lysine]
Gene, Accession #n/a
Catalog #MBS8004223
Price$525
Order / More InfoAcetylated Lysine Antibody from MYBIOSOURCE INC.
Product Specific References1. Yang X.J. (2005) Oncogene. 24:1653-1662. 2. Hassig C.A. and Schreiber S.L. (1997) Curr. Opin. Chem. Biol. 1(3): 300-308. 3. Yang X.J. (2004) Bioessays 26:1076-1087. 4. Hughes R.E. (2002) Curr. Biol. 12: R141-R143. 5. Vigushin D.M. and Coombes R.C. (2004) Curr. Cancer Drug Targets 4: 205-218. 6. Chan H.M. et al. (2001) Nat. Cell Biol. 3: 667-674. 7. Martinez-Balbas M.A. et al. (2000) EMBO J. 19: 662-671.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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