Edit |   |
---|---|
Antigenic Specificity | CD68, 133-160 |
Clone | [404CT9.2.5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CD68 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from human CD68. This gene encodes a 110-kD transmembrane glycoprotein thatis highly expressed by human monocytes and tissue macrophages. Itis a member of the lysosomal/endosomal-associated membraneglycoprotein (LAMP) family. The protein primarily localizes tolysosomes and endosomes with a smaller fraction circulating to thecell surface. It is a type I integral membrane protein with aheavily glycosylated extracellular domain and binds to tissue- andorgan-specific lectins or selectins. The protein is also a memberof the scavenger receptor family. Scavenger receptors typicallyfunction to c |
Immunogen | n/a |
Other Names | [Macrosialin; Gp110; CD68; CD68] |
Gene, Accession # | [CD68], Gene ID: 968, NCBI: NP_001035148.1, UniProt: P34810 |
Catalog # | MBS9200304 |
Price | $370 |
Order / More Info | CD68, 133-160 Antibody from MYBIOSOURCE INC. |
Product Specific References | Leonarduzzi, G., et al. Mol Nutr Food Res 54 SUPPL 1, S31-S41 (2010) : Strojnik, T., et al. Anticancer Res. 29(8):3269-3279(2009) Sayed, S., et al. Eur J Vasc Endovasc Surg 38(1):20-25(2009) Suzuki, Y., et al. Int J Rheum Dis 12(1):7-13(2009) Chen, W.S., et al. Scand. J. Rheumatol. 38(2):154-155(2009) |