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Antigenic Specificity | Irak1, ID (Irak1, Il1rak, Interleukin-1 receptor-associated kinase 1, Pelle-like protein kinase) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1mg/ml |
Applications | ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human IRAK1/IRAK. IRAK1, an IRAK type protein kinase, is a signal transducer for the immune response Toll-like receptor and interleukin-1 (IL-1) receptor signaling cascades. IRAK1 is recruited to the IL-1 receptor, phosphorylated and progressively degraded in response to IL-1 induction. The protein also has the ability to autophosphorylate. IRAK1 is immediately downstream of the MyD88 adapter protein and immediately upstream of TRAF6. IRAK1 (-/-) mice have impaired responses to interleukin-18. At least two mRNA transcript variants have been identified - 2.0 and 3.6 kb. |
Immunogen | Immunogen: Synthetic peptide corresponding to human IRAK1/IRAK. |
Other Names | [-Irak1, ID (Irak1, Il1rak, Interleukin-1 receptor-associated kinase 1, Pelle-like protein kinase)] |
Gene, Accession # | Gene ID: 3654, NCBI: NP_001020414.1, UniProt: P51617 |
Catalog # | MBS6000633 |
Price | $695 |
Order / More Info | Irak1, ID (Irak1, Il1rak, Interleukin-1 receptor-associated kinase 1, Pelle-like protein kinase) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |