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Antigenic Specificity | Integrin beta 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Integrin beta 3 Antibody detects endogenous levels of total Integrin beta 3. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity). |
Immunogen | Immunogen: A synthesized peptide derived from human Integrin beta 3 |
Other Names | [CD61; GP3A; GPIIIa; Integrin beta-3; integrin; beta 3 (platelet glycoprotein IIIa; antigen CD61); ITGB3], [ITGB3; ITGB3; GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16; GP3A; GPIIIa] |
Gene, Accession # | [ITB3], Gene ID: 3690, NCBI: NP_000203.2, UniProt: P05106 |
Catalog # | MBS477955 |
Price | $335 |
Order / More Info | Integrin beta 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |