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Antigenic Specificity | DNAJB14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DNAJB14 antibody detects endogenous levels of DNAJB14. Function: Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway (PubMed:24732912). Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities (PubMed:24732912). Can also act independently of HSPA8/Hsc70: together with DNAJB12, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers (PubMed:27916661). While stabilization of nascent channel proteins is dependent on HSPA8/Hsc70, the process |
Immunogen | Immunogen: A synthesized peptide derived from human DNAJB14. Subcellular Location: Endoplasmic Reticulum; Nucleus Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (89%) |
Other Names | [5730496F10Rik; DJB14_HUMAN; DnaJ (Hsp40) homolog, subfamily B, member 14; DnaJ homolog subfamily B member 14; dnajb14; EGNR9427; FLJ14281; MGC22187; PRO34683; UNQ9427/PRO34683] |
Gene, Accession # | [DNAJB14], Gene ID: 79982, NCBI: NP_001026893.1, UniProt: Q8TBM8 |
Catalog # | MBS9603426 |
Price | $240, $280 |
Order / More Info | DNAJB14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |