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Antigenic Specificity | Phospho-VAV3(Tyr173) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-VAV3(Tyr173) antibody detects endogenous levels of VAV3 only when phosphorylated at Tyrosine 173. Description: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]Function: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser exten |
Immunogen | Immunogen: A synthesized peptide derived from human VAV3 around the phosphorylation site of Tyrosine 173 Tissue Specificity: Isoform 1 and isoform 3 are widely expressed; both are expressed at very low levels in skeletal muscle. In keratinocytes, isoform 1 is less abundant than isoform 3. Isoform 3 is detected at very low levels, if any, in adrenal gland, bone marrow, spleen, fetal brain and spinal chord; in these tissues, isoform 1 is readily detectable. |
Other Names | [FLJ40431; Guanine nucleotide exchange factor VAV3; Protein vav 3; Protein vav3; RGD1565941; VAV 3; Vav 3 guanine nucleotide exchange factor; VAV 3 oncogene; VAV 3 protein; VAV-3; Vav3; VAV3 oncogene; VAV3 protein; VAV3_HUMAN] |
Gene, Accession # | [VAV3], Gene ID: 10451, NCBI: NP_001073343.1, UniProt: Q9UKW4 |
Catalog # | MBS9600032 |
Price | $240, $280 |
Order / More Info | Phospho-VAV3(Tyr173) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |