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Antigenic Specificity | IPO9 (N-term), 79-106 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This IPO9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-106 amino acids from the N-terminal region of human IPO9. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases |
Immunogen | n/a |
Other Names | [Importin-9; Imp9; Ran-binding protein 9; RanBP9; IPO9; IMP9; KIAA1192; RANBP9] |
Gene, Accession # | [IPO9], Gene ID: 55705, NCBI: NP_060555.2, UniProt: Q96P70 |
Catalog # | MBS9211793 |
Price | $165, $370 |
Order / More Info | IPO9 (N-term), 79-106 Antibody from MYBIOSOURCE INC. |
Product Specific References | King, F.W., et al. Mol. Cell. Biol. 24(16):7091-7101(2004) Lubert, E.J., et al. Biochem. Biophys. Res. Commun. 303(3):908-913(2003) Jakel, S., et al. EMBO J. 21(3):377-386(2002) Muhlhausser, P., et al. EMBO Rep. 2(8):690-696(2001) |