GILT, Mouse Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGILT, Mouse
CloneMaP.mGILT6
Host SpeciesMouse
Reactive Speciesmouse
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsFlow Ctometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
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DescriptionAntibodies derived from clone MaP.mGILT6 recognize mouse gamma-interferon-inducible lysosomal thiol reductase (GILT). GILT facilitates major histocompatibility complex (MHC) class II-restricted processing through reduction of protein disulfide bonds in the endocytic pathway. GILT can also facilitate the transfer of disulfide-containing antigens into the cytosol, enhancing their cross-presentation by MHC class I. Human GILT consists of 261 amino acids with a 37 amino acid signal sequence and a 224 amino acid precursor form. In general, the 35 kDa precursor is tagged with mannose-6- phosphate (M6P) residues and transported to the endocytic pathway via the M6P receptor (M6PR). A small fraction of the precursor is secreted as a disulfide-linked
ImmunogenImmunogen: Insect-cell expressed recombinant mouse GILT
Other Namesn/a
Gene, Accession #[GILT]
Catalog #MBS584662
Price$420
Order / More InfoGILT, Mouse Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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