5HT2B Receptor Antibody from MYBIOSOURCE INC.

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Antigenic Specificity5HT2B Receptor
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDescription: Rabbit IgG polyclonal antibody for 5-hydroxytryptamine receptor 2B(HTR2B) detection. Tested with WB in Human;Rat. Background: 5HT2B Receptor is known as HTR2B. This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2B Receptor (446-478aa MRLRSSTIQSSSIILLDTLLLTENEGDKTEEQ V), different from the related mouse sequence by six amino acids, and from the related rat sequence by nine amino acids. Ig Type: Rabbit IgG
Other Names[5-hydroxytryptamine receptor 2B; 5 HT 2B; 5 HT 2B receptor; 5 HT(2B); 5 HT2B; 5 hydroxytryptamine (serotonin) receptor 2B; 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled; 5 hydroxytryptamine 2B receptor; 5 hydroxytryptamine receptor 2B; 5-HT-2B; 5-HT2B; 5-hydroxytryptamine receptor 2B; 5HT(2B); 5HT2B_HUMAN; 5HT2F; Htr 2b; Htr2b; NP75 protein; SEROTONIN 5HT2B RECEPTOR; Serotonin receptor 2B; Stomach fundus serotonin receptor; 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled], [HTR2B; HTR2B; 5-HT2B; 5-HT-2B; 5-HT(2B); 5-HT-2B; 5-HT2B]
Gene, Accession #Gene ID: 3357, NCBI: NP_000858.3, UniProt: P41595
Catalog #MBS177864
Price$280
Order / More Info5HT2B Receptor Antibody from MYBIOSOURCE INC.
Product Specific References1. Entrez Gene: HTR2B 5-hydroxytryptamine (serotonin) receptor 2B. 2. Doly S, Valjent E, Setola V, Callebert J, Herve D, Launay JM, Maroteaux L (Mar 2008). Serotonin 5-HT2B receptors are required for 3,4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro. The Journal of Neuroscience28 (11): 2933-40. 3. Schmuck K, Ullmer C, Engels P, Lubbert H (Mar 1994). Cloning and functional characterization of the human 5-HT2B serotonin receptor. FEBS Letters 342 (1): 85-90.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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