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Antigenic Specificity | 5HT2B Receptor |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for 5-hydroxytryptamine receptor 2B(HTR2B) detection. Tested with WB in Human;Rat. Background: 5HT2B Receptor is known as HTR2B. This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2B Receptor (446-478aa MRLRSSTIQSSSIILLDTLLLTENEGDKTEEQ V), different from the related mouse sequence by six amino acids, and from the related rat sequence by nine amino acids. Ig Type: Rabbit IgG |
Other Names | [5-hydroxytryptamine receptor 2B; 5 HT 2B; 5 HT 2B receptor; 5 HT(2B); 5 HT2B; 5 hydroxytryptamine (serotonin) receptor 2B; 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled; 5 hydroxytryptamine 2B receptor; 5 hydroxytryptamine receptor 2B; 5-HT-2B; 5-HT2B; 5-hydroxytryptamine receptor 2B; 5HT(2B); 5HT2B_HUMAN; 5HT2F; Htr 2b; Htr2b; NP75 protein; SEROTONIN 5HT2B RECEPTOR; Serotonin receptor 2B; Stomach fundus serotonin receptor; 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled], [HTR2B; HTR2B; 5-HT2B; 5-HT-2B; 5-HT(2B); 5-HT-2B; 5-HT2B] |
Gene, Accession # | Gene ID: 3357, NCBI: NP_000858.3, UniProt: P41595 |
Catalog # | MBS177864 |
Price | $280 |
Order / More Info | 5HT2B Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: HTR2B 5-hydroxytryptamine (serotonin) receptor 2B. 2. Doly S, Valjent E, Setola V, Callebert J, Herve D, Launay JM, Maroteaux L (Mar 2008). Serotonin 5-HT2B receptors are required for 3,4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro. The Journal of Neuroscience28 (11): 2933-40. 3. Schmuck K, Ullmer C, Engels P, Lubbert H (Mar 1994). Cloning and functional characterization of the human 5-HT2B serotonin receptor. FEBS Letters 342 (1): 85-90. |