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Antigenic Specificity | CK1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CK1 antibody detects endogenous levels of total CK1. Description: CK1 (also designated Cytokeratin 1 or KRT1), with 644-amino acid protein (about 70kDa), is a member of the keratin family. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells.CK1 consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK1 is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderm |
Immunogen | Immunogen: Purified recombinant fragment of human CK1 expressed in E. Coli Subcellular Location: Cytoplasm. Cytoplasm > Cytoskeleton > Centrosome. Chromosome > Centromere > Kinetochore. Nucleus Speckle. Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. |
Other Names | [Casein kinase 1 alpha 1; Casein kinase I isoform alpha; CK1; CK1A; CKI alpha; CKI-alpha; CKIa; Clock regulator kinase; Csnk1a1; Down regulated in lung cancer; HLCDGP1; KC1A_HUMAN; PRO2975] |
Gene, Accession # | [CK1], Gene ID: 1452, NCBI: NP_001020276.1, UniProt: P48729 |
Catalog # | MBS9602411 |
Price | $235, $295, $370 |
Order / More Info | CK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Wang X, Bao H, Liu X, Wang C, Hao C; Journal: Oncol Lett. Effects of endometrial stem cell transplantation combined with estrogen in the repair of endometrial injury. |