PDE3B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPDE3B
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: PDE3B antibody detects endogenous levels of total PDE3B. Function: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.Subunit Structure: Interacts with PIK3CG (By similarity). Interacts with RAPGEF3 and PIK3R6.Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily.
ImmunogenImmunogen: A synthesized peptide derived from human PDE3B Subcellular Location: Membrane. Tissue Specificity: Abundant in adipose tissues.
Other Names[5''-cyclic phosphodiesterase B; Adipocyte cAMP phosphodiesterase cGMP inhibited; AI847709; cAMP Phosphodiesterase, adipocyte, cGMP-inhibited; CGI-PDE B; CGIP1; CGIPDE B; CGIPDE1; cGMP inhibited 3 5 cyclic phosphodiesterase B; CGMP inhibited cAMP phophodiesterase; cGMP-inhibited 3''; Cyclic GMP inhibited phosphodiesterase B; Cyclic GMP-inhibited phosphodiesterase B; Cyclic nucleotide phosphodiesterase; HcGIP1; HcGIP1, rat, homolog of; Pde3b; PDE3B_HUMAN; Phosphodiesterase 3B; Phosphodiesterase 3B cGMP inhibited]
Gene, Accession #[PDE3B], Gene ID: 5140, NCBI: NP_000913.2, UniProt: Q13370
Catalog #MBS9609689
Price$240, $280
Order / More InfoPDE3B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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