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Antigenic Specificity | PDE3B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PDE3B antibody detects endogenous levels of total PDE3B. Function: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.Subunit Structure: Interacts with PIK3CG (By similarity). Interacts with RAPGEF3 and PIK3R6.Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily. |
Immunogen | Immunogen: A synthesized peptide derived from human PDE3B Subcellular Location: Membrane. Tissue Specificity: Abundant in adipose tissues. |
Other Names | [5''-cyclic phosphodiesterase B; Adipocyte cAMP phosphodiesterase cGMP inhibited; AI847709; cAMP Phosphodiesterase, adipocyte, cGMP-inhibited; CGI-PDE B; CGIP1; CGIPDE B; CGIPDE1; cGMP inhibited 3 5 cyclic phosphodiesterase B; CGMP inhibited cAMP phophodiesterase; cGMP-inhibited 3''; Cyclic GMP inhibited phosphodiesterase B; Cyclic GMP-inhibited phosphodiesterase B; Cyclic nucleotide phosphodiesterase; HcGIP1; HcGIP1, rat, homolog of; Pde3b; PDE3B_HUMAN; Phosphodiesterase 3B; Phosphodiesterase 3B cGMP inhibited] |
Gene, Accession # | [PDE3B], Gene ID: 5140, NCBI: NP_000913.2, UniProt: Q13370 |
Catalog # | MBS9609689 |
Price | $240, $280 |
Order / More Info | PDE3B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |