HSP70 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHSP70
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, beluga, bovine, dog, fish, carp, guinea pig, hamster, monkey, porcine, sheep, coral, plant, shark, L. amazonensis
Isotypen/a
FormatAPC-Cy7 conjugate
Size0.1 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA (EIA)
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DescriptionDetects a ~70 kDa. May cross-react with HSC70 at lower dilutions. HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 50% identity (1, 2). The N-terminal two thirds of HSP70s are more conserved than the C-terminal third. HSP70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides (3). When HSC70 (constitutively expressed) present in mammalian
ImmunogenImmunogen: Full length protein HSP70
Other Names[Rabbit Human HSP70; HSP70 1; HSP70 2; HSP70.1; HSP72; HSP73; HSPA1; HSPA1A; HSPA1B]
Gene, Accession #[HSP70], Gene ID: 3303, NCBI: NP_005336.3, UniProt: P0DMV8
Catalog #MBS8004055
Price$510
Order / More InfoHSP70 Antibody from MYBIOSOURCE INC.
Product Specific References1. Welch W.J. and Suhan J.P. (1986) J.Cell Biol. 103: 2035-2050. 2. Boorstein W. R., Ziegelhoffer T. & Craig E. A. (1993) J. Mol. Evol. 38(1): 1-17. 3. Rothman J. (1989) Cell 59: 591-601. 4. DeLuca-Flaherty et al. (1990) Cell 62: 875-887. 5. Bork P., Sander C. & Valencia A. (1992) Proc. Nut1 Acad. Sci. USA 89: 7290-7294. 6. Fink A.L. (1999) Physiol. Rev. 79: 425-449. 7. Hung T.H., et al. (2001) Am J Pathol. 159: 1031-1043. 8. Locke M. (2000) Cell Stress & Chaperones 5: 45-51. 9. Ianaro A., et al. (2001) FEBS Lett. 508: 61-66. 10. Trentin G.A. et al. (2001) J Biol Chem. 276: 13087-13095.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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