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Antigenic Specificity | SIPA1 (C-term), 942-970 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.3 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SIPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 942-970 amino acids from the C-terminal region of human SIPA1. The product of this gene is a mitogen induced GTPaseactivating protein (GAP). It exhibits a specific GAP activity forRas-related regulatory proteins Rap1 and Rap2, but not for Ran orother small GTPases. This protein may also hamper mitogen-inducedcell cycle progression when abnormally or prematurely expressed. Itis localized to the perinuclear region. Two alternatively splicedvariants encoding the same isoform have been characterized to date. |
Immunogen | n/a |
Other Names | [Signal-induced proliferation-associated protein 1; Sipa-1; GTPase-activating protein Spa-1; p130 SPA-1; SIPA1; SPA1] |
Gene, Accession # | [SIPA1], Gene ID: 6494, NCBI: NP_006738.3, UniProt: Q96FS4 |
Catalog # | MBS9208449 |
Price | $165, $370 |
Order / More Info | SIPA1 (C-term), 942-970 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Brooks, R., et al. Gynecol. Oncol. 116(3):539-543(2010) Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Hsieh, S.M., et al. Breast Cancer Res. 11 (5), R75 (2009) : |