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Antigenic Specificity | ATG5 |
Clone | 3C7 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous ATG5 protein. ATG5, also named as APG5L and ASP, belongs to the ATG5 family. It is required for autophagy. It plays an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. It mediates autophagosome-independent host protection. |
Immunogen | Immunogen: Recombinant Protein of ATG5 |
Other Names | [Mouse ATG5 Mouse (3C7); Autophagy protein 5; APG5-like; Apoptosis-specific protein] |
Gene, Accession # | [ATG5], Gene ID: 9474, NCBI: Q9H1Y0.2, UniProt: Q9H1Y0 |
Catalog # | MBS9700339 |
Price | $250, $250 |
Order / More Info | ATG5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |