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Antigenic Specificity | CD3E |
Clone | [4E2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. |
Immunogen | Immunogen: Purified recombinant fragment of CD3E expressed in E Coli. |
Other Names | [T3E; TCRE; FLJ18683; CD3E], [T3E; TCRE; FLJ18683; CD3E] |
Gene, Accession # | [CD3E], Gene ID: 916, NCBI: EAW67364.1 |
Catalog # | MBS476007 |
Price | $335 |
Order / More Info | CD3E Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |