Human 2-5A-dependent ribonuclease Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human 2-5A-dependent ribonuclease |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | fluorescein (FITC) conjugate |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes. RNASEL mediated apoptosis is the result of a JNK-dependent stress-response pathway leading to cytochrome c release from mitochondria and caspase-dependent apoptosis. Therefore, activation of RNASEL could lead to elimination of virus infected cells under some circumstances. Might play a central role in the regulation of mRNA turnover. |
| Immunogen | Immunogen: Recombinant human 2-5A-dependent ribonuclease protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22871 / sc-22870 / sc-25798 |
| Other Names | [2-5A-dependent RNase; Ribonuclease 4; Ribonuclease L; RNase L; RNASEL; RNS4], [RNASEL; RNASEL; RNS4; PRCA1; RNS4; 2-5A-dependent RNase; RNase L] |
| Gene, Accession # | Gene ID: 6041, NCBI: NP_066956.1, UniProt: Q05823 |
| Catalog # | MBS1489387 |
| Price | $160, $235 |
| Order / More Info | Human 2-5A-dependent ribonuclease Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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