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Antigenic Specificity | Down Syndrome Cell Adhesion Molecule (DSCAM) (DS2-176) |
Clone | [DS2-176] |
Host Species | Mouse |
Reactive Species | chicken, mouse |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: A specific antibody against the chicken Dscam C-terminal region (amino acids 1207 to 1527). Down syndrome cell adhesion molecule (Dscam) is a cell adhesion molecule that plays a role in neuronal self-avoidance. It promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Dscam mediates, within retinal amacrine and ganglion cell subtypes, both isoneuronal selfavoidance for creating an orderly dendritic arborization and heteroneuronal selfavoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies. It is the receptor for netrin that is required for axon guidance independently of and in collaboration with the receptor DCC. In spinal cord development, it play |
Immunogen | n/a |
Other Names | [Dscam, partial; Dscam; Dscam], [dscam] |
Gene, Accession # | [DSCAM], NCBI: AII71685.1 |
Catalog # | MBS588022 |
Price | $425 |
Order / More Info | Down Syndrome Cell Adhesion Molecule (DSCAM) (DS2-176) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Yamagata M and Sanes JR-Dscam and Sidekick proteins direct lamina-specific synaptic connections invertebrate retina. Transfected human embryonic kidney 293 cells, overexpressing chicken Dscam or mouse Dscam, fixed with 4% paraformaldehyde/PBS. Cells are labeled with anti-Dscam antibody. |